产品货号：
Z17499
中文名称：
Granzyme A/GZMA抗体
英文名称：
Anti-Granzyme A/GZMA Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Granzyme A/GZMA Antibody |
| 指标别名 | CTL tryptase;CTLA3;Fragmentin 1;GrA;Granzyme 1;Granzyme A;GZMA;H factor;Hanukkah factor;HF;HFSP |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC |
| 基因名称 | GZMA |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence in the middle region of human Granzyme A(175-190aa DRKVCNDRNHYNFNPV). |
| 实际分子量 | 36KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Granzyme A is a protein that in humans is encoded by the GZMA gene.Cytolytic T lymphocytes(CTL) and natural killer(NK) cells share the remarkable ability to recognize,bind,and lyse specific target cells.They are though to protect their host by lysing cells bearing on their surface "nonself" antigens,usually peptides or proteins resulting from infection by intracellular pathogens.The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells.GZMA induces caspase-independent apoptosis in a characteristic manner,except it causes a distinctive form of DNA damage:single-stranded DNA nicking.A target of GZMA is the SET complex,including HMGB2 and ANP32A. |
| Uniprot ID | P12544 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | granzyme A(granzyme 1,cytotoxic T-lymphocyte-associated serine esterase 3) |
| 蛋白名全称 | Granzyme A |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
相关搜索：Granzyme A/GZMA抗体，Granzyme A抗体，GZMA多抗，Anti-Granzyme A/GZMA Antibody